Prof. Dr. Ilkay YILDIZ'ın web sitesine hosgeldiniz.
 

International Journal Articles


 

01. İsmail YALÇIN, İlkay ÖREN, Esin ŞENER, Ahmet AKIN, Nejat UÇARTÜRK; “The synthesis and the structure-activity relationships of some substituted benzoxazoles, oxazolo(4,5-b)pyridines, benzothiazoles and benzimidazoles as antimicrobial agents” European Journal of Medicinal Chemistry, 27: 401-406, (1992).

02. Esin ŞENER, Hülya TURGUT, İsmail YALÇIN, İlkay ÖREN, Lemi TÜRKER, Nihat ÇELEBİ, Ahmet AKIN; “Structure-activity relationships of some antimicrobial 5-substituted-2-(3-pyridyl)benzoxazoles using quantum-chemical calculations” International Journal of  Pharmaceutics, 110: 109-115, (1994).  

03. Esin ŞENER, İsmail YALÇIN, Özlem TEMİZ, İlkay ÖREN, Ahmet AKIN, Nejat UÇARTÜRK;  “Synthesis and Structure-Activity Relationships of some 2,5-disubstituted Benzoxazoles and Benzimidazoles as Antimicrobial Agents” Il Farmaco, 52(2): 99-103 (1997).  

04. İlkay ÖREN, Özlem TEMİZ, İsmail YALÇIN, Esin ŞENER, Ahmet AKIN, Nejat UÇARTÜRK; “Synthesis and Microbiological Activity of 5 (or 6)-methyl-2-substituted Benzoxazole and Benzimidazole Derivatives” Arzneimittel-Forschung/Drug Research, 47(12): 1393-1397 (1997).  

05. İsmail YALÇIN, Bedia KOÇYİĞİT KAYMAKÇIOĞLU, İlkay ÖREN, Esin ŞENER, Özlem TEMİZ, Ahmet AKIN, Nurten ALTANLAR;  “Synthesis and Microbiological activity of some novel N-(2-hydroxyl-5-substitutedphenyl) benzacetamides, phenoxyacetamides and thiophenoxyacetamides as the possible metabolites ofantimicrobial active benzoxazoles” Il Farmaco, 52(11): 685-689 (1997).  

06. Çelik TarImcI, Filiz ERCAN, Meltem KOÇOĞLU, İlkay ÖREN; “N-[(2-Hydroxy-5-chloro)phenyl]thiophenylacetamide” Acta Crystallographica Section C,  C54: 488-489 (1998).  

07. Özlem TEMİZ, İlkay ÖREN, Esin ŞENER, İsmail YALÇIN, Nejat UÇARTÜRK; “Synthesis and microbiological activity of some novel 5- or 6-methyl-2-(2,4-disubstitutedphenyl)benzoxazole derivatives” Il Farmaco,  53: 337-341 (1998).  

08. İlkay ÖREN, Özlem TEMİZ, İsmail YALÇIN, Esin ŞENER, Nurten ALTANLAR; “Synthesis and antimicrobial activity of some novel 2,5- and/or 6-substituted benzoxazole and benzimidazole derivatives” European Journal of Pharmaceutical Sciences, 7: 153-160 (1998).  

09. Esin AKI ŞENER, Kamuran K. BİNGÖL, İlkay ÖREN, Özlem TEMİZ ARPACI, İsmail YALÇIN, Nurten ALTANLAR; “Synthesis and microbiological activity of some N-(o-hydroxyphenyl)benzamides and phenylacetamides as the possible metabolites of antimicrobial  active benzoxazoles, Part II” Il Farmaco, 55: 469-476 (2000).

10. İsmail YALÇIN, İlkay ÖREN, Özlem TEMİZ and Esin AKI-ŞENER; “QSARs of some novel isosteric heterocyclics with antifungal activity” Acta Biochimica Polonica, 47(2): 481-486 (2000).  

11. Özlem TEMİZ ARPACI, İlkay ÖREN, Nurten ALTANLAR; “Synthesis and antimicrobial activity of some novel 2-(p-substituted-phenyl)-5-substituted-carbonylaminobenzoxazoles” Il Farmaco,  57: 175-181 (2002).  

12. David C. Lankin, Gary L. Grunewald, F. Anthony Romero, Ilkay Yıldız Oren, James P. Snyder; “The NH¾FC Dipole Orientation Effect for Pendant Exocylic CH2Organic Letters, 4(21): 3557-3560 (2002).

13. Ayşegül AKBAY, İlkay ÖREN, Özlem TEMİZ, Esin AKI-ŞENER, İsmail YALÇIN; “Synthesis and HIV-1 Reverse Transcriptase Inhibitor Activity of Some 2,5,6-Substituted Benzoxazole, Benzimidazole, Benzothiazole and Oxazolo(4,5-b(pyridine Derivatives” Arzneimittel-Forschung/Drug Research,  53(4): 266-271 (2003).

14. İsmail YALÇIN, Betul B. TEKİNER, İlkay YILDIZ-ÖREN, Özlem TEMİZ-ARPACI, Esin AKI-ŞENER, Nurten ALTANLAR; “Synthesis and antimicrobial activity of some novel 2,6,7-trisubstituted-2H-3,4-dihydro-1,4-benzoxazin-3-one derivatives” Indian Journal of Chemistry, Vol. 42B: 905-909 (2003).

15. İlkay YILDIZ-ÖREN, Betül TEKİNER-GÜLBAŞ, Özlem TEMİZ-ARPACI, İsmail YALÇIN, Esin AKI-ŞENER; “3D-QSAR CoMFA studies on 2-(p-substitutedbenzyl)-5-(substitutedcarbonylamino)benzoxazoles as antibacterial agents against Staphylococcus aureus” Asian Journal of Chemistry, Vol 16, Nos. 3-4, 1359-1366 (2004).  

16. İlkay YILDIZ-ÖREN, İsmail YALÇIN, Esin AKI-ŞENER, Nejat UÇARTÜRK; “Synthesis and structure-activity relationships of new antimicrobial active multisubstituted benzazole derivatives” European Journal of Medicinal Chemistry,  39, 291-298 (2004).  

17. İlkay YILDIZ-ÖREN, Esin AKI-ŞENER, Cengiz ERTAŞ, Özlem TEMİZ-ARPACI, İsmail YALÇIN, Nurten ALTANLAR; “Synthesis and microbiological activity of some substituted N-(2-hydroxy-4-nitrophenyl)benzamides and phenylacetamides as the possible metabolites of antimicrobial active benzoxazoles” Turkish Journal of Chemistry 28, 441-449 (2004)  

18. Asli Pinar, Pinar Yurdakul , İlkay Yildiz , Ozlem Temiz-Arpaci , N. Leyla Acan , Esin Aki-Sener and Ismail Yalcin ”Some fused heterocyclic compounds as eukaryotic topoisomerase II inhibitors”, Biochemical and Biophysical Research Communications, Volume 317, Issue 2,  670-674 (2004).
 

19. Richard K. Plemper,   Karl J. Erlandson, Ami S. Lakdawala, Aming Sun, Andrew Prussia, Jutatip BoonsombaT, Esin Aki-Sener, Ismail Yalcin , İlkay Yildiz, Ozlem Temiz-Arpaci, Betul Tekiner, Dennis Liotta, James P. Snyder, Richard W. Compans  "A Novel Target Site for Template-Based Design of Measles Virus Entry Inhibitors"  PNAS (Proceedings of the National Academy of Sciences of the United States of America)  101(15), 5628-5633 (2004).

20. İlkay YILDIZ-OREN, Betul TEKINER, Ismail YALCIN, Ozlem TEMIZ-ARPACI, Esin AKI-SENER, Nurten ALTANLAR; “Synthesis and antimicrobial activity of new 2-[p-substituted-benzyl]-5-[substituted-carbonylamino]benzoxazoles” Archiv der Pharmazie , 337(7), 402-410 (2004).

21. Özlem Temiz-ArpacI, Aliye Özdemir, İsmail YalÇIn,  İlkay YIldIz, Esin Akı-Şener, Nurten Altanlar “Synthesis and antimicrobial activity of some new benzoxazoles” Arch. Pharm. Chem. Life Sci. 338, 105-111 (2005).  

22. Özlem TEMIZ-ARPACI, Betül TEKİNER-GÜLBAS, İlkay YILDIZ, Esin AKI-ŞENER, İsmail YALÇIN, "3D-QSAR Analysis on Benzazole Derivatives as Eukaryotic Topoisomerase II Inhibitors by Using Comparative Molecular Field Analysis Method" Bioorganic & Medicinal Chemistry, 13, 6354-6359, (2005).

23. UGUR, Y., AKBAY-YARPUZLU, A., NAZIKOGLU, A., ASAN, E., YILDIZ, I., KELES, S., "Investigating Toxic Effects of the HIV-RT Inhibitor 2-Phenoxymethyl-5-chloro-benzimidazole on Rat Liver", Turkish Journal of Medical Sciences , 35(1), 5-12, (2005).

24. TEKINER-GULBAS, B., TEMIZ-ARPACI, O., YILDIZ, I., AKI-SENER, E., YALCIN, I., “3D-QSAR Study on Heterocyclic Topoisomerase II Inhibitors using CoMSIA”, SAR and QSAR in Enviromental Research, 17(2), 121-132, (2006).

25. TEMIZ-ARPACI, O., COBAN, T., TEKINER-GULBAS, B., CAN-EKE, B., YILDIZ, İ., AKI-SENER, E., YALCIN, I., ISCAN, M., “A Study on the Antioxidant Activities of Some New Benzazole Derivatives”, Acta Biol. Hungarica, 57(2), 201-209, (2006).

26. ALPER-HAYTA, S., AKI-SENER, E., TEKINER-GULBAS, B., YILDIZ, I., TEMIZ-ARPACI, O., YALCIN, I., ALTANLAR, N., “Synthesis, Antimicrobial Activity and QSARs of New Benzoxazine-3-ones”, Eur. J. Med. Chem., (2006).

27. TEMİZ-ARPACI, Ö., TEKINER-GULBAS, B., YILDIZ, İ., AKI-ŞENER, E., YALCIN, İ., "3D-QSAR Analysis on Benzazole Derivatives as Eukaryotic Topoisomerase II Inhibitors by using Comparative Molecular Field Analysis Method", QSAR and Molecular Modelling in Rational Design of Bioactive Molecules, Istanbul-Turkey, September 5-10, 2004, AKI-ŞENER, E., YALÇIN, İ. (Eds.), Başkent Publishing, Ankara, (2006).

28. ANTO, P.L., PANICKER, C.Y., VARGHESE, H.T., PHILIP, D., TEMIZ-ARPACI, O., TEKINER-GULBAS, B., YILDIZ, I., “Vibrational spectroscopic studies and ab initio calculations of 5-methyl-2-(p-fluorophenyl)benzoxazole”, Spectrochimica Acta Part A, Aug 25, (2006).

29. ERTAN, T., YILDIZ, I., OZKAN, S., TEMIZ-ARPACI, O., KAYNAK, F., YALCIN, I., AKI-SENER, E., ABBASOGLU, U., "Synthesis and Biological Evaluation of New n-(2-Hydroxy-4(or 5)-nitro/ aminophenyl)benzamides and Phenylacetamides as Antimicrobial Agents", Bioorganic and Medicinal Chemistry, 15, 2032-2044, (2007).

30. TEKINER-GULBAS, B., TEMIZ-ARPACI, O., YILDIZ, I., ALTANLAR, N., "Synthesis and In Vitro Antimicrobial Activity of New 2-[p-Substituted-benzyl]-5-[substituted-carbonylamino]benzoxazoles", European Journal of Medicinal Chemistry, in press, (2007).

31. TEKINER-GULBAS, B., TEMIZ-ARPACI, O., OKSUZOGLU, E., EROGLU, H., YILDIZ, I., DIRIL, N., AKI-SENER, E., YALCIN, I., "QSAR of Genotoxic Active Benzazoles", SAR and QSAR in Environmental Research, 18, 251–263, (2007).

32. Ambujakshan KR, Madhavan VS, Varghese HT, Panicker CY, Temiz-Arpaci O, Tekiner-Gulbas B, Yildiz I., "Vibrational spectroscopic studies and ab initio calculations of 5-methyl-2-(p-methylaminophenyl)benzoxazole", Spectrochim Acta A Mol Biomol Spectrosc., 2007.

33. Emine Oksuzoglu; Betul Tekiner-Gulbas; Sabiha Alper; Ozlem Temiz-Arpaci; Tugba Ertan; Ilkay Yildiz; Nuran Diril; Esin Sener-Aki; Ismail Yalcin, "Some benzoxazoles and benzimidazoles as DNA topoisomerase I and II inhibitors", Journal of Enzyme Inhibition and Medicinal Chemistry, 2007.

 

National Journal Articles


   

34. İsmail YALÇIN, Esin ŞENER, İlkay ÖREN; “QSAR of Some Antibacterial Active Isosteric Heterocyclic Compounds Against An Enterobacter” Trends in QSAR and Molecular Modelling 92, C.G. Wermuth (Ed.), Escom, Leiden , pp: 570-572 (1993). 

35. İsmail YALÇIN, Esin ŞENER, İlkay ÖREN, Özlem TEMİZ; “Determination of the Activity Contrubutions of Some Novel Isosteric Heterocyclics Against an Enteric Gram-Negative Rod Using the Free-Wilson Analysis” QSAR and Molecular Modelling, Concepts: Computational Tools and Biological Applications, F. Sanz, J. Giraldo and F. Manaut (Eds.), Prous Science Publishers, pp: 147-151, (1995).  

36. Esin ŞENER, Özlem TEMİZ, İlkay ÖREN, İsmail YALÇIN, Ahmet AKIN, Nejat UÇARTÜRK; “Synthesis, Antibacterial Activity and QSAR's of some 5-Substituted-2-(p-Substitutedbenzyl)benzoxazoles using the Free-Wilson Analysis” Ankara Üniversitesi Eczacılık Fakültesi Dergisi, 24 (1): 10-20, (1995).

37. İlkay ÖREN; “QSAR of some antifungal active benzoxazoles and benzimidazoles against C. albicans” Ankara Üniversitesi Eczacılık Fakültesi Dergisi 27(1): 1-9 (1998). 

38. Asriye MOCAN, Filiz KUNTAY, Funda TUĞCU, İlkay ÖREN; “Oral Cerrahi Girisimlerde Intaranazal Midazolam Uygulanmasi” Ankara Üniversitesi Diş Hekimliği Fakültesi Dergisi, 27(3): 291-296 (2000). 

39. OREN, İ., TEMIZ-ARPACI, Ö., YALÇIN, İ., AKI-ŞENER, “QSARs of Some Novel Benzoxazole, Benzimidazole and Oxazolo(4,5-b)pyridine Derivatives against C. albicans”, J. Fac. Pharm. Ankara, 31(1), 21-32, (2002).

40. TEMIZ-ARPACI, Ö., OREN, İ., AKI-ŞENER, E., YALÇIN, İ., TEKINER, B., “QSARs of Some Antibacterial Active Benzoxazoles against  B. subtilis”, J. Fac. Pharm., Ankara, 31(2), 73-81, (2002).

41. YILDIZ-ÖREN, İ., TEKİNER-GÜLBAŞ, B.P., “DFT Calculations of Some Antimicrobial Active 3,4-Dihydro-1,4-benzoxazin-3-one Derivatives”, J. Fac. Pharm. Ankara, 32(3), 165-173, (2003).

42. AKBAY-YARPUZLU, A., YILDIZ, İ., TEMIZ-ARPACI, Ö., KARAGENÇ, N., AKI-ŞENER, E., YALÇIN, İ.,  “Adenosine Deaminase Inhibitor Activity of Some Benzoxazole, Benzimidazole, and Oxazolo(4,5-b)pyridine Derivatives”, XIII. Biotecnological Congress Proceedings Book, Çanakkale, 21-26, (2003). 

 

Reviews


   

01. İlkay ÖREN, İsmail YALÇIN ; “Yeni Bir Antibiyotik, Kalsimisin” Ankara Üniversitesi Eczacılık Fakültesi Dergisi, 21(1-2): 53-65 (1992). 

02. İlkay ÖREN, İsmail YALÇIN ; “Kemoterapötik Etkili Benzoxazole Türevleri ve Halka Analogları Üzerinde Gerçekleştirilmiş Yapı-Etki İlişkileri” Ankara Üniversitesi Eczacılık Fakültesi Dergisi, 25: 81-106 (1996).

 

Oral Presentations


   

01. ŞENER, E., TEMİZ, Ö., ÖREN, İ., YALÇIN, İ., ALTANLAR, N., Synthesis and QSAR Analysis of Some Novel 2,5-Disubstituted Benzoxazoles Against B. subtilis., Second International Meeting on Pharmacy and Pharmaceutical Sciences, İstanbul, Turkey, Abstracts O9, 06-09 September 1998.

02. ŞENER, E., ÖREN, İ., TEMİZ-ARPACI, Ö., BİNGÖL, K. K., YALÇIN, İ., QSARs of Some Novel Antibacretial Active Isosteric Heterocyclics Against Bacillus Subtilis., 2nd International Symposium on Pharmaceutical Chemistry, Ankara, Turkey, Abstract O-23, 22-24 September 1999.

03. ŞENER, E., ÖREN, İ., ARPACI-TEMİZ, YALÇIN, i., “3-D QSAR of Some Antibacterial Active Heterocyclic Compounds Using the CoMSIA Method” 6th International Symposium on Pharmaceutical Sciences, Ankara, Turkey, Abstracts 136, 27-29 September 2000.

04. AKI-ŞENER, E., YALÇIN, İ., YILDIZ, İ., TEMİZ-ARPACI, Ö., ALPER, S., ZAFER, B., “Studies on Pharmacophore Group Identification of Topoisomerase II Inhibitory Active Fused Heterocyclics Using CATALYST HipHop”, The European Cost Action B16 Symposium on Multidrug Resistance Reversal, Antalya” Abstracts  19, 13-14 May, 2005.

05. AKI-ŞENER, E., YALÇIN, İ., YILDIZ, I., TEMİZ ARPACI, Ö., ZAFER, B., TEKİNER-GÜLBAŞ; B., “3D-QSAR Studies of Topoisomerase II Inhibitors Using Catalyst ” Watoc`05, Modelling Structure and Reactivity 7th Congress of the World Association of Theoretically Oriented Chemists, Cape Town, South Africa, Abstract C12-5, 16-21 January 2005.

06. YILDIZ, I., YALÇIN, İ., AKI-ŞENER, E.,  TEMİZ ARPACI, Ö., TEKİNER-GÜLBAŞ;  B., “3D-QSAR Studies on Some Topoisomerase II Inhibitors”  3rd International Symposium Computational Methods In Toxicology &Pharmacology Integrating Internet Resources (CMTPI-2005), Shanghai, P.R: China,  Abstract  ORB-06, October 29th- November 1st, 2005.

07. Yalçın, İ., Akı-Şener, E., Yıldız, İ. “Studies on pharmacophore identification of topoisomerase II inhibitors using catalyst HipHop” 18 Conferincia de quimica Santiago de Cuba, Cuba, TM-PO2, Abstract page 6-9 December 2005.

08. TEMİZ ARPACI, Ö., ÖKSÜZOĞLU, e., TEKİNER-GÜLBAŞ; B., ZAFER, B., YILDIZ, I., DİRİL, N., AKI-ŞENER, E., YALÇIN, İ., “Genotoxic activities and QSAR studies of some benzoxazoles and benzimidazoles”, QSAR 2006-12th International Workshop on Quantitative Structure-Activity Relationships in Enviromental Toxicology , Lyon, France,  Abstract s O -67 , 8-12 May 2006.

09. YALÇIN, İ., AKI-ŞENER, E., YILDIZ, I., TEMİZ ARPACI, Ö., TEKİNER-GÜLBAŞ; B., “Research results incorporated on COST B16 Action from the year 2003 to 2006”, European Conference on the Reversal of Multidrug Resistance from Bacteria to Cancer Cells and Parasites, Budapest, Hungary, Abstracts OP-04, 22-25 April 2006.

10. AKI-ŞENER, E., YALÇIN, İ., ALPER-HAYTA, S., TEKİNER-GÜLBAŞ; B., TEMİZ ARPACI, Ö., YILDIZ, I., ALTANLAR, N., “Synthesis, antimicrobial activity and QSARs of New Benzoxazine-3-ones”, European Conference on the Reversal of Multidrug Resistance from Bacteria to Cancer Cells and Parasites, Budapest, Hungary, Abstracts OP-10, 22-25 April 2006.

11. Pınar, A., Yurdakul, P., Temiz-Arpacı, O., Tekiner-Gulbas, B., Yıldız,  I., Akı-Sener, E., Yalcın, İ., İleri, O., “Eukaryotic Topoisomerase II activity of some novel fused heterocyclic compounds”, 31st FEBS Congress, İstanbul, Turkey, 24-29 June 2006.

12. TEMİZ ARPACI, Ö., ÖKSÜZOĞLU, e., TEKİNER-GÜLBAŞ; B., ZAFER, B., YILDIZ, I., DİRİL, N., AKI-ŞENER, E., YALÇIN, İ., “Genotoxic activities and QSAR studies of some benzoxazoles and benzimidazoles”, QSAR 2006-12th International Workshop on Quantitative Structure-Activity Relationships in Enviromental Toxicology , Lyon, France,  Abstract s O -67 , 8-12 May 2006.

13. YILDIZ, I., ALPER, S., ERTAN, T., TEMIZ-ARPACI, O., TEKINER-GULBAS, B., AKI-SENER, E., YALCIN, I., "Molecular Modeling Studies on Some Eucaryotic Topoisomerase II Enzyme Inhibitor Fused Heterocyclic Compounds", 6th AFMC International Medicinal Chemistry Symposium", Istanbul-TURKEY, July 08-11, 2007.